1MKK

Disulfide deficient mutant of vascular endothelial growth factor A (C61A and C104A)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Vascular Endothelial Growth Factor A	polymer	96	11196.0	2	UniProt (P15692) Pfam (PF00341)	Homo sapiens (human)	VEGF-A, Vascular permeability factor, VPF
2	C, D (A, B)	water	water		18.0	205	Chemie (HOH)

Sequence modifications

A, B: 14 - 108 (UniProt: P15692)

PDB	External Database	Details
Met 13	-	cloning artifact
Ala 61	Cys 87	engineered mutation
Ala 104	Cys 130	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	22391.9
All*	Total formula weight	22391.9

*Water molecules are not included.