1MH0
Crystal structure of the anticoagulant slow form of thrombin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Prothrombin | polymer | 287 | 33007.9 | 2 | UniProt (P00734) Pfam (PF09396) Pfam (PF00089) | Homo sapiens (human) | Alpha-thrombin; coagulation factor II |
| 2 | C, D (A, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 3 | E, F (A, B) | water | water | 18.0 | 111 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 245 (UniProt: P00734)
| PDB | External Database | Details |
|---|---|---|
| Ala 77 | Arg 436 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 66015.8 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 442.4 | |
| All* | Total formula weight | 66458.2 |
