1MEU

HIV-1 MUTANT (V82F, I84V) PROTEASE COMPLEXED WITH DMP323

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	HIV-1 PROTEASE	polymer	99	10823.7	2	UniProt (P03366) Pfam (PF00077) In PDB	Human immunodeficiency virus 1
2	A	[4-R-(-4-ALPHA,5-ALPHA,6-BETA,7-BETA)]-HEXAHYDRO-5,6-BIS(HYDROXY)-[1,3-BIS([4-HYDROXYMETHYL-PHENYL]METHYL)-4,7-BIS(PHEN YLMETHYL)]-2H-1,3-DIAZEPINONE	non-polymer		566.7	1	Chemie (DMP)

Sequence modifications

A, B: 1 - 99 (UniProt: P03366)

PDB	External Database	Details
Phe 82	Val 138	engineered mutation
Val 84	Ile 140	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	21647.5
Non-Polymers*	Number of molecules	1
	Total formula weight	566.7
All*	Total formula weight	22214.2

*Water molecules are not included.