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1MAR

REFINED 1.8 ANGSTROMS STRUCTURE OF HUMAN ALDOSE REDUCTASE COMPLEXED WITH THE POTENT INHIBITOR ZOPOLRESTAT

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
ALDOSE REDUCTASEpolymer31535767.11UniProt (P15121)
Pfam (PF00248)
Homo sapiens (human)
2B
(A)
NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATEnon-polymer743.41Chemie (NAP)
3C
(A)
3,4-DIHYDRO-4-OXO-3-((5-TRIFLUOROMETHYL-2-BENZOTHIAZOLYL)METHYL)-1-PHTHALAZINE ACETIC ACIDnon-polymer419.41Chemie (ZST)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight35767.1
Non-Polymers*Number of molecules2
Total formula weight1162.8
All*Total formula weight36929.9
*Water molecules are not included.

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PDB entries from 2025-12-17

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