1M93

1.65 A Structure of Cleaved Viral Serpin CRMA

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Serine proteinase inhibitor 2	polymer	55	6079.8	1	UniProt (P07385)	Cowpox virus	cytokine response modifier protein A, Serpin 2, Serp-2, ICE inhibitor, Hemorrhage-inducing 38 kDa protein
2	B (B)	Serine proteinase inhibitor 2	polymer	245	27403.8	1	UniProt (P07385) Pfam (PF00079)	Cowpox virus	cytokine response modifier protein A, Serpin 2, Serp-2, ICE inhibitor, Hemorrhage-inducing 38 kDa protein
3	C (C)	Serine proteinase inhibitor 2	polymer	41	4518.0	1	UniProt (P07385)	Cowpox virus	cytokine response modifier protein A, Serpin 2, Serp-2, ICE inhibitor, Hemorrhage-inducing 38 kDa protein
4	D (A)	PHOSPHATE ION	non-polymer		95.0	1	Chemie (PO4)
5	E, F, G (A, B, C)	water	water		18.0	146	Chemie (HOH)

Sequence modifications

B: 56 - 300 (UniProt: P07385)

PDB	External Database	Details
Ser 93	Cys 93	engineered mutation
Ser 102	Cys 102	engineered mutation
Ser 124	Cys 124	engineered mutation
Ser 223	Cys 223	engineered mutation
Ser 269	Cys 269	engineered mutation
Ser 298	Cys 298	engineered mutation

C: 301 - 341 (UniProt: P07385)

PDB	External Database	Details
Ser 304	Cys 304	engineered mutation
Ser 313	Cys 313	engineered mutation
Ser 336	Cys 336	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	38001.6
Non-Polymers*	Number of molecules	1
	Total formula weight	95.0
All*	Total formula weight	38096.5

*Water molecules are not included.