1M79
Candida albicans Dihydrofolate Reductase Complexed with Dihydro-Nicotinamide-Adenine-Dinucleotide Phosphate (NADPH) and 5-(4-methoxyphenoxy)-2,4-quinazolinediamine (GW1466)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | dihydrofolate reductase | polymer | 192 | 22194.5 | 2 | UniProt (P22906) Pfam (PF00186) | Candida albicans | DHFR |
| 2 | C, F (A, B) | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 745.4 | 2 | Chemie (NDP) | |||
| 3 | D, G (A, B) | 5-(4-METHOXYPHENOXY)-2,4-QUINAZOLINEDIAMINE | non-polymer | 282.3 | 2 | Chemie (MQ1) | |||
| 4 | E, H (A, B) | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID | non-polymer | 195.2 | 2 | Chemie (MES) | |||
| 5 | I, J (A, B) | water | water | 18.0 | 354 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 44389.1 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 2445.9 | |
| All* | Total formula weight | 46835.0 |
