1M6B
Structure of the HER3 (ERBB3) Extracellular Domain
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Receptor protein-tyrosine kinase erbB-3 | polymer | 621 | 68376.5 | 2 | UniProt (P21860) Pfam (PF01030) Pfam (PF00757) Pfam (PF14843) In PDB | Homo sapiens (human) | Growth Factor Receptor Extracellular Domain; c-erbB3; Tyrosine kinase-type cell surface receptor HER3; epidermal growth factor receptor; v-erb-b2 erythroblastic leukemia viral oncogene homolog |
| 2 | C, D | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
| 3 | A, B | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 13 | Chemie (NAG) | |||
| 4 | B | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 5 | water | water | 18.0 | 85 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 621 (UniProt: P21860)
| PDB | External Database | Details |
|---|---|---|
| Val 61 | Ile 80 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 136753.1 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 848.8 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 2971.8 | |
| All* | Total formula weight | 140573.7 |
