1M5P

Transition State Stabilization by a Catalytic RNA

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D	RNA INHIBITOR SUBSTRATE	polymer	12	3810.4	2
2	M, P	RNA INHIBITOR SUBSTRATE	polymer	9	2683.1	2
3	B, E	RNA HAIRPIN RIBOZYME	polymer	92	29809.8	2
4	C, F	U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A	polymer	100	11498.5	2	UniProt (P09012) Pfam (PF00076) In PDB	Homo sapiens (human)	U1 snRNP A protein; U1 snRNP-specific protein A
5	E, C, F, B, P	CALCIUM ION	non-polymer		40.1	26	Chemie (CA)
6		water	water		18.0	45	Chemie (HOH)

Sequence modifications

C, F: 1 - 100 (UniProt: P09012)

PDB	External Database	Details
His 31	Tyr 31	engineered mutation
Arg 36	Gln 36	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	95603.5
Non-Polymers*	Number of molecules	26
	Total formula weight	1042.0
All*	Total formula weight	96645.5

*Water molecules are not included.