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1M5F

X-RAY STRUCTURE OF THE GLUR2 LIGAND BINDING CORE (S1S2J-Y702F) IN COMPLEX WITH ACPA AT 1.95 A RESOLUTION

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, CGlutamate receptor 2polymer26329205.73UniProt (P19491)
Pfam (PF10613)
Pfam (PF00060)
In PDB
Rattus norvegicus (Norway rat)GLUR-2, GLUR-B, GLUR-K2, GLUTAMATE RECEPTOR IONOTROPIC AMPA 2
2A, B, CZINC IONnon-polymer65.46Chemie (ZN)
3A, B, C(S)-2-AMINO-3-(3-CARBOXY-5-METHYLISOXAZOL-4-YL)PROPIONIC ACIDnon-polymer214.23Chemie (AM1)
4BACETATE IONnon-polymer59.01Chemie (ACT)
5waterwater18.0852Chemie (HOH)
Sequence modifications
A, B, C: 3 - 117 (UniProt: P19491)
PDBExternal DatabaseDetails
Gly 1-cloning artifact
Ala 2-cloning artifact
A, B, C: 120 - 263 (UniProt: P19491)
PDBExternal DatabaseDetails
Gly 118-linker
Thr 119-linker
Phe 190Tyr 723engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight87617.0
Non-Polymers*Number of molecules10
Total formula weight1094.0
All*Total formula weight88711.1
*Water molecules are not included.

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PDB entries from 2024-07-03

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