1M5F
X-RAY STRUCTURE OF THE GLUR2 LIGAND BINDING CORE (S1S2J-Y702F) IN COMPLEX WITH ACPA AT 1.95 A RESOLUTION
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Glutamate receptor 2 | polymer | 263 | 29205.7 | 3 | UniProt (P19491) Pfam (PF10613) Pfam (PF00060) | Rattus norvegicus (Norway rat) | GLUR-2, GLUR-B, GLUR-K2, GLUTAMATE RECEPTOR IONOTROPIC AMPA 2 |
| 2 | D, G, H, I, J... (A, B, C) | ZINC ION | non-polymer | 65.4 | 6 | Chemie (ZN) | |||
| 3 | E, K, M (A, B, C) | (S)-2-AMINO-3-(3-CARBOXY-5-METHYLISOXAZOL-4-YL)PROPIONIC ACID | non-polymer | 214.2 | 3 | Chemie (AM1) | |||
| 4 | F (B) | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) | |||
| 5 | N, O, P (A, B, C) | water | water | 18.0 | 852 | Chemie (HOH) |
Sequence modifications
A, B, C: 3 - 117 (UniProt: P19491)
A, B, C: 120 - 263 (UniProt: P19491)
| PDB | External Database | Details |
|---|---|---|
| Gly 1 | - | cloning artifact |
| Ala 2 | - | cloning artifact |
| PDB | External Database | Details |
|---|---|---|
| Gly 118 | - | linker |
| Thr 119 | - | linker |
| Phe 190 | Tyr 723 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 87617.0 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 1094.0 | |
| All* | Total formula weight | 88711.1 |
