1M4B
Crystal Structure of Human Interleukin-2 K43C Covalently Modified at C43 with 2-[2-(2-Cyclohexyl-2-guanidino-acetylamino)-acetylamino]-N-(3-mercapto-propyl)-propionamide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | interleukin-2 | polymer | 133 | 15409.9 | 1 | UniProt (P60568) Pfam (PF00715) | Homo sapiens (human) | IL-2, T-CELL GROWTH FACTOR, TCGF, ALDESLEUKIN |
| 2 | B (A) | 2-[2-(2-CYCLOHEXYL-2-GUANIDINO-ACETYLAMINO)-ACETYLAMINO]-N-(3-MERCAPTO-PROPYL)-PROPIONAMIDE | non-polymer | 400.5 | 1 | Chemie (NMP) | |||
| 3 | C (A) | water | water | 18.0 | 19 | Chemie (HOH) |
Sequence modifications
A: 1 - 133 (UniProt: P60568)
| PDB | External Database | Details |
|---|---|---|
| Cys 43 | Lys 63 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 15409.9 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 400.5 | |
| All* | Total formula weight | 15810.5 |
