1M4A
Crystal Structure of Human Interleukin-2 Y31C Covalently Modified at C31 with (1H-Indol-3-yl)-(2-mercapto-ethoxyimino)-acetic acid
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | interleukin-2 | polymer | 133 | 15375.9 | 1 | UniProt (P60568) Pfam (PF00715) | Homo sapiens (human) | IL-2, T-CELL GROWTH FACTOR, TCGF, ALDESLEUKIN |
| 2 | B (A) | (1H-INDOL-3-YL)-(2-MERCAPTO-ETHOXYIMINO)-ACETIC ACID | non-polymer | 266.3 | 1 | Chemie (MPE) | |||
| 3 | C (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 4 | D (A) | water | water | 18.0 | 13 | Chemie (HOH) |
Sequence modifications
A: 1 - 133 (UniProt: P60568)
| PDB | External Database | Details |
|---|---|---|
| Cys 31 | Tyr 51 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 15375.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 358.4 | |
| All* | Total formula weight | 15734.4 |
