1M49

Crystal Structure of Human Interleukin-2 Complexed with SP-1985

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	interleukin-2	polymer	133	15436.0	2	UniProt (P60568) Pfam (PF00715)	Homo sapiens (human)	IL-2, T-CELL GROWTH FACTOR, TCGF, ALDESLEUKIN
2	C, D (A, B)	2-[2-(1-CARBAMIMIDOYL-PIPERIDIN-3-YL)-ACETYLAMINO]-3-{4-[2-(3-OXALYL-1H-INDOL-7-YL)ETHYL]-PHENYL}-PROPIONIC ACID METHYL ESTER	non-polymer		561.6	2	Chemie (CMM)
3	E, F (A, B)	water	water		18.0	104	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	30872.0
Non-Polymers*	Number of molecules	2
	Total formula weight	1123.3
All*	Total formula weight	31995.2

*Water molecules are not included.