1M43
Crystal structure of PMII in complex with pepstatin a to 2.4 A
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B (A, B) | plasmepsin II | polymer | 331 | 37079.8 | 2 | UniProt (P46925) Pfam (PF00026) | Plasmodium falciparum (malaria parasite P. falciparum) | Aspartic hemoglobinase II, PFAPD |
2 | C, D (C, D) | Pepstatin | polymer | 6 | 685.9 | 2 | BIRD (PRD_000557) | Streptomyces argenteolus subsp. toyonakensis | |
3 | E, F, G, H (A, B, C, D) | water | water | 18.0 | 555 | Chemie (HOH) |
Sequence modifications
A, B: -1 - 329 (UniProt: P46925)
PDB | External Database | Details |
---|---|---|
Ser 205 | Met 329 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 75531.4 | |
All* | Total formula weight | 75531.4 |