1M2T
Mistletoe Lectin I from Viscum album in Complex with Adenine Monophosphate. Crystal Structure at 1.9 A Resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | mistletoe lectin I A chain | polymer | 254 | 27820.1 | 1 | UniProt (P81446) Pfam (PF00161) In PDB | Viscum album (European mistletoe) | Beta-galactoside specific lectin I A chain; MLA; ML-I A; rRNA N-glycosidase |
| 2 | B | mistletoe lectin I B chain | polymer | 263 | 28568.9 | 1 | UniProt (P81830) Pfam (PF00652) UniProt (by SIFTS) (P81446) In PDB | Viscum album (European mistletoe) | lectin chain A isoform 1 |
| 3 | A, B | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 6 | Chemie (NAG) | |||
| 4 | A, B | alpha-L-fucopyranose | non-polymer | 164.2 | 2 | Chemie (FUC) | |||
| 5 | A | ADENINE | non-polymer | 135.1 | 1 | Chemie (ADE) | |||
| 6 | A, B | GLYCEROL | non-polymer | 92.1 | 8 | Chemie (GOL) | |||
| 7 | water | water | 18.0 | 503 | Chemie (HOH) |
Sequence modifications
A: 1 - 254 (UniProt: P81446)
B: 248 - 510 (UniProt: P81830)
| PDB | External Database | Details |
|---|---|---|
| Thr 8 | Val 8 | conflict |
| Asp 9 | Thr 9 | conflict |
| Gln 10 | His 10 | conflict |
| Ala 15 | Glu 15 | conflict |
| Ser 19 | Arg 19 | conflict |
| Val 23 | Leu 23 | conflict |
| Asn 36 | Glu 36 | conflict |
| Val 45 | Ile 45 | conflict |
| Glu 49 | Asp 49 | conflict |
| Gly 50 | Ala 50 | conflict |
| Ala 61 | Gln 61 | conflict |
| Gly 63 | Gln 63 | conflict |
| Thr 65 | Ser 65 | conflict |
| Ile 66 | Val 66 | conflict |
| Leu 75 | Ala 75 | conflict |
| Glu 81 | Gln 81 | conflict |
| Asn 84 | Asp 84 | conflict |
| Ser 90 | Arg 90 | conflict |
| Ala 94 | Arg 94 | conflict |
| Gln 99 | His 99 | conflict |
| Asp 100 | Leu 100 | conflict |
| Ser 102 | Thr 102 | conflict |
| Ser 106 | Arg 106 | conflict |
| Gln 109 | Leu 109 | conflict |
| Gln 148 | Ser 148 | conflict |
| Lys 150 | Arg 150 | conflict |
| Ala 176 | Tyr 176 | conflict |
| Ala 219 | Arg 219 | conflict |
| Ala 223 | Pro 223 | conflict |
| Val 226 | Asn 226 | conflict |
| Ile 227 | Phe 227 | conflict |
| Ile 233 | Val 233 | conflict |
| PDB | External Database | Details |
|---|---|---|
| Ala 249 | Asp 2 | conflict |
| Thr 253 | Ser 6 | conflict |
| Ile 258 | Thr 11 | conflict |
| Thr 268 | Arg 21 | conflict |
| Lys 301 | Arg 54 | conflict |
| Gly 342 | Asp 95 | conflict |
| Thr 390 | Val 143 | conflict |
| Ala 403 | Asn 156 | conflict |
| Tyr 408 | Trp 161 | conflict |
| Thr 413 | Asp 166 | conflict |
| Ala 414 | Ser 167 | conflict |
| Gly 415 | Ser 168 | conflict |
| Glu 417 | Lys 170 | conflict |
| - | Gly 173 | deletion |
| Arg 420 | Lys 174 | conflict |
| Leu 434 | Asn 188 | conflict |
| Ser 436 | Asp 190 | conflict |
| Asn 441 | Ser 195 | conflict |
| Ile 446 | Val 200 | conflict |
| Ala 457 | - | insertion |
| Ser 459 | Ala 212 | conflict |
| - | Ser 215 | deletion |
| Ser 489 | Lys 243 | conflict |
| Gln 491 | Arg 245 | conflict |
| Asn 501 | Lys 255 | conflict |
| Pro 510 | Phe 264 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 56389.0 | |
| Non-Polymers* | Number of molecules | 17 |
| Total formula weight | 2527.4 | |
| All* | Total formula weight | 58916.4 |
