1LYA
CRYSTAL STRUCTURES OF NATIVE AND INHIBITED FORMS OF HUMAN CATHEPSIN D: IMPLICATIONS FOR LYSOSOMAL TARGETING AND DRUG DESIGN
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C | CATHEPSIN D | polymer | 97 | 10688.9 | 2 | UniProt (P07339) In PDB | Homo sapiens (human) | |
2 | B, D | CATHEPSIN D | polymer | 241 | 26270.2 | 2 | UniProt (P07339) Pfam (PF00026) In PDB | Homo sapiens (human) | |
3 | E, F | alpha-D-mannopyranose-(1-6)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 748.7 | 2 | In PDB GlyTouCan (G22573RC) | |||
4 | B, D | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
5 | water | water | 18.0 | 46 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 73918.3 | |
Branched | Number of molecules | 2 |
Total formula weight | 1497.4 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 442.4 | |
All* | Total formula weight | 75858.1 |