1LWU

Crystal structure of fragment D from lamprey fibrinogen complexed with the peptide Gly-His-Arg-Pro-amide

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D, G, J	Fibrinogen alpha-1 chain	polymer	119	14074.1	4	UniProt (P02674) Pfam (PF08702) In PDB	Petromyzon marinus (Sea lamprey)
2	B, E, H, K	Fibrinogen beta chain	polymer	323	37061.2	4	UniProt (P02678) In PDB	Petromyzon marinus (Sea lamprey)
3	C, F, I, L	Fibrinogen gamma chain	polymer	323	37475.6	4	UniProt (P04115) Pfam (PF08702) Pfam (PF00147) In PDB	Petromyzon marinus (Sea lamprey)
4	M, N, O, P	Peptide Ligand Gly-His-Arg-Pro-NH2	polymer	5	465.5	4
5	Q	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	1	In PDB GlyTouCan (G42666HT)
6	O, H, B, K, M...	2-acetamido-2-deoxy-alpha-D-glucopyranose	non-polymer		221.2	9	Chemie (NDG)
7	E, P, F, H, B...	alpha-D-mannopyranose	non-polymer		180.2	10	Chemie (MAN)
8	E, F, H, I, B...	CALCIUM ION	non-polymer		40.1	8	Chemie (CA)
9	F, I, C, E	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	7	Chemie (NAG)
10	E, H	beta-D-mannopyranose	non-polymer		180.2	2	Chemie (BMA)
11	H	beta-D-galactopyranose	non-polymer		180.2	1	Chemie (GAL)

Sequence modifications

A, D, G, J: 82 - 200 (UniProt: P02674)

PDB	External Database	Details
Ala 153	Thr 158	conflict

C, F, I, L: 79 - 401 (UniProt: P04115)

PDB	External Database	Details
Pro 137	Ser 161	conflict

Contents of the asymmetric unit

Polymers	Number of chains	16
	Total formula weight	356305.4
Branched	Number of molecules	1
	Total formula weight	424.4
Non-Polymers*	Number of molecules	37
	Total formula weight	6202.0
All*	Total formula weight	362931.8

*Water molecules are not included.