1LTX
Structure of Rab Escort Protein-1 in complex with Rab geranylgeranyl transferase and isoprenoid
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | RAB GERANYLGERANYLTRANSFERASE ALPHA SUBUNIT | polymer | 567 | 64981.2 | 1 | UniProt (Q08602) Pfam (PF01239) Pfam (PF07711) | Rattus norvegicus (Norway rat) | |
| 2 | B (B) | RAB GERANYLGERANYLTRANSFERASE BETA SUBUNIT | polymer | 331 | 36892.2 | 1 | UniProt (Q08603) Pfam (PF00432) | Rattus norvegicus (Norway rat) | Geranylgeranyl transferase type II beta subunit |
| 3 | C (R) | Rab Escort Protein 1 | polymer | 650 | 72594.2 | 1 | UniProt (P37727) Pfam (PF00996) Pfam (PF22603) | Rattus norvegicus (Norway rat) | Rab proteins geranylgeranyltransferase component A 1 |
| 4 | D (P) | AAAA | polymer | 4 | 302.3 | 1 | |||
| 5 | E (B) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 6 | F (R) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 7 | G (P) | FARNESYL | non-polymer | 206.4 | 1 | Chemie (FAR) | |||
| 8 | H, I, J, K (A, B, R, P) | water | water | 18.0 | 103 | Chemie (HOH) |
Sequence modifications
R: 1 - 650 (UniProt: P37727)
| PDB | External Database | Details |
|---|---|---|
| Lys 231 | Gln 231 | engineered mutation |
| Thr 473 | Ala 473 | engineered mutation |
| Ala 483 | Gly 483 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 174769.9 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 307.2 | |
| All* | Total formula weight | 175077.1 |
