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1LTX

Structure of Rab Escort Protein-1 in complex with Rab geranylgeranyl transferase and isoprenoid

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
RAB GERANYLGERANYLTRANSFERASE ALPHA SUBUNITpolymer56764981.21UniProt (Q08602)
Pfam (PF01239)
Pfam (PF07711)
Rattus norvegicus (Norway rat)
2B
(B)
RAB GERANYLGERANYLTRANSFERASE BETA SUBUNITpolymer33136892.21UniProt (Q08603)
Pfam (PF00432)
Rattus norvegicus (Norway rat)Geranylgeranyl transferase type II beta subunit
3C
(R)
Rab Escort Protein 1polymer65072594.21UniProt (P37727)
Pfam (PF00996)
Pfam (PF22603)
Rattus norvegicus (Norway rat)Rab proteins geranylgeranyltransferase component A 1
4D
(P)
AAAApolymer4302.31
5E
(B)
ZINC IONnon-polymer65.41Chemie (ZN)
6F
(R)
CHLORIDE IONnon-polymer35.51Chemie (CL)
7G
(P)
FARNESYLnon-polymer206.41Chemie (FAR)
8H, I, J, K
(A, B, R, P)
waterwater18.0103Chemie (HOH)
Sequence modifications
R: 1 - 650 (UniProt: P37727)
PDBExternal DatabaseDetails
Lys 231Gln 231engineered mutation
Thr 473Ala 473engineered mutation
Ala 483Gly 483engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight174769.9
Non-Polymers*Number of molecules3
Total formula weight307.2
All*Total formula weight175077.1
*Water molecules are not included.

238268

PDB entries from 2025-07-02

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