1LT8
Reduced Homo sapiens Betaine-Homocysteine S-Methyltransferase in Complex with S-(delta-carboxybutyl)-L-Homocysteine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | BETAINE-HOMOCYSTEINE METHYLTRANSFERASE | polymer | 406 | 44844.0 | 2 | UniProt (Q93088) Pfam (PF02574) | Homo sapiens (human) | BETAINE-HOMOCYSTEINE S-METHYLTRANSFERASE |
| 2 | C, F (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | D, G (A, B) | S-(D-CARBOXYBUTYL)-L-HOMOCYSTEINE | non-polymer | 235.3 | 2 | Chemie (CBH) | |||
| 4 | E, H (A, B) | CITRIC ACID | non-polymer | 192.1 | 2 | Chemie (CIT) | |||
| 5 | I, J (A, B) | water | water | 18.0 | 431 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 406 (UniProt: Q93088)
| PDB | External Database | Details |
|---|---|---|
| Ala 2 | Pro 2 | engineered mutation |
| Ala 104 | Cys 104 | engineered mutation |
| Ala 131 | Cys 131 | engineered mutation |
| Ala 186 | Cys 186 | engineered mutation |
| Ala 201 | Cys 201 | engineered mutation |
| Gln 239 | Arg 239 | SEE REMARK 999 |
| Ala 256 | Cys 256 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 89688.0 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 985.7 | |
| All* | Total formula weight | 90673.7 |
