1LT8

Reduced Homo sapiens Betaine-Homocysteine S-Methyltransferase in Complex with S-(delta-carboxybutyl)-L-Homocysteine

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	BETAINE-HOMOCYSTEINE METHYLTRANSFERASE	polymer	406	44844.0	2	UniProt (Q93088) Pfam (PF02574) In PDB	Homo sapiens (human)	BETAINE-HOMOCYSTEINE S-METHYLTRANSFERASE
2	A, B	ZINC ION	non-polymer		65.4	2	Chemie (ZN)
3	A, B	S-(D-CARBOXYBUTYL)-L-HOMOCYSTEINE	non-polymer		235.3	2	Chemie (CBH)
4	A, B	CITRIC ACID	non-polymer		192.1	2	Chemie (CIT)
5		water	water		18.0	431	Chemie (HOH)

Sequence modifications

A, B: 1 - 406 (UniProt: Q93088)

PDB	External Database	Details
Ala 2	Pro 2	engineered mutation
Ala 104	Cys 104	engineered mutation
Ala 131	Cys 131	engineered mutation
Ala 186	Cys 186	engineered mutation
Ala 201	Cys 201	engineered mutation
Gln 239	Arg 239	SEE REMARK 999
Ala 256	Cys 256	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	89688.0
Non-Polymers*	Number of molecules	6
	Total formula weight	985.7
All*	Total formula weight	90673.7

*Water molecules are not included.