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1LS3

Crystal Structure of the Complex between Rabbit Cytosolic Serine Hydroxymethyltransferase and TriGlu-5-formyl-tetrahydrofolate

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C, D
(A, B, C, D)
Serine Hydroxymethyltransferasepolymer48352916.14UniProt (p07511)
Pfam (PF00464)
UniProt (by SIFTS) (P07511)
Oryctolagus cuniculus (rabbit)SERINE METHYLASE, GLYCINE HYDROXYMETHYLTRANSFERASE, SHMT
2E, G, L, N
(A, B, C, D)
PYRIDOXAL-5'-PHOSPHATEnon-polymer247.14Chemie (PLP)
3F, K
(A, C)
GLYCINEnon-polymer75.12Chemie (GLY)
4H, O
(B, D)
2-[4-(4-{4-[(2-AMINO-5-FORMYL-4-OXO-3,4,5,6,7,8-HEXAHYDRO-PTERIDIN-6-YLMETHYL)-AMINO]-BENZOYLAMINO}-4-CARBOXY-BUTYRYLAM INO)-4-CARBOXY-BUTYRYLAMINO]-PENTANEDIOIC ACIDnon-polymer731.72Chemie (TGF)
5I, J, M, P
(B, C, D)
GLYCEROLnon-polymer92.14Chemie (GOL)
6Q, R, S, T
(A, B, C, D)
waterwater18.0378Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight211664.5
Non-Polymers*Number of molecules12
Total formula weight2970.4
All*Total formula weight214634.9
*Water molecules are not included.

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PDB entries from 2025-06-18

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