1LQV
Crystal structure of the Endothelial protein C receptor with phospholipid in the groove in complex with Gla domain of protein C.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Endothelial protein C receptor | polymer | 193 | 22046.6 | 2 | UniProt (Q9UNN8) Pfam (PF16497) | Homo sapiens (human) | Endothelial cell protein C receptor, Activated protein C receptor, APC receptor |
| 2 | C, D (C, D) | Vitamin-K dependent protein C | polymer | 33 | 4359.4 | 2 | UniProt (P04070) Pfam (PF00594) | Homo sapiens (human) | Autoprothrombin IIA, Anticoagulant protein C, Blood coagulation factor XIV |
| 3 | E, F, G, I, J... (A, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 6 | Chemie (NAG) | |||
| 4 | H, L (A, B) | PHOSPHATIDYLETHANOLAMINE | non-polymer | 734.0 | 2 | Chemie (PTY) | |||
| 5 | M, N, O, P, Q... (C, D) | CALCIUM ION | non-polymer | 40.1 | 14 | Chemie (CA) | |||
| 6 | AA, BA, CA, DA (A, B, C, D) | water | water | 18.0 | 429 | Chemie (HOH) |
Sequence modifications
C, D: 1 - 33 (UniProt: P04070)
| PDB | External Database | Details |
|---|---|---|
| Cgu 6 | Glu 48 | modified residue |
| Cgu 7 | Glu 49 | modified residue |
| Cgu 14 | Glu 56 | modified residue |
| Cgu 16 | Glu 58 | modified residue |
| Cgu 19 | Glu 61 | modified residue |
| Cgu 20 | Glu 62 | modified residue |
| Cgu 25 | Glu 67 | modified residue |
| Cgu 26 | Glu 68 | modified residue |
| Cgu 29 | Glu 71 | modified residue |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 52811.9 | |
| Non-Polymers* | Number of molecules | 22 |
| Total formula weight | 3356.4 | |
| All* | Total formula weight | 56168.4 |
