1LQS
CRYSTAL STRUCTURE OF HUMAN CYTOMEGALOVIRUS IL-10 BOUND TO SOLUBLE HUMAN IL-10R1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (R, S) | INTERLEUKIN-10 RECEPTOR ALPHA CHAIN | polymer | 214 | 24506.6 | 2 | UniProt (Q13651) Pfam (PF01108) | Homo sapiens (human) | IL-10R-A, IL-10R1 |
| 2 | C, D (L, M) | INTERLEUKIN-10-LIKE PROTEIN | polymer | 157 | 18141.6 | 2 | UniProt (P17150) Pfam (PF00726) | Human herpesvirus 5 (Human cytomegalovirus) | |
| 3 | E, F (L, M) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 4 | G, H, I, J (R, S, L, M) | water | water | 18.0 | 48 | Chemie (HOH) |
Sequence modifications
R, S: 1 - 214 (UniProt: Q13651)
| PDB | External Database | Details |
|---|---|---|
| Gln 29 | Asn 50 | engineered mutation |
| Gln 53 | Asn 74 | engineered mutation |
| Gln 89 | Asn 110 | engineered mutation |
| Gln 133 | Asn 154 | engineered mutation |
| Gln 156 | Asn 177 | engineered mutation |
| Gln 168 | Asn 189 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 85296.4 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 442.4 | |
| All* | Total formula weight | 85738.8 |
