1L4D

CRYSTAL STRUCTURE OF MICROPLASMINOGEN-STREPTOKINASE ALPHA DOMAIN COMPLEX

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	PLASMINOGEN	polymer	249	27248.3	1	UniProt (P00747) Pfam (PF00089) In PDB	Homo sapiens (human)
2	B	STREPTOKINASE	polymer	122	13456.0	1	UniProt (P00779) Pfam (PF02821) In PDB	Streptococcus dysgalactiae subsp. equisimilis
3	A	SULFATE ION	non-polymer		96.1	2	Chemie (SO4)
4		water	water		18.0	213	Chemie (HOH)

Sequence modifications

A: 543 - 791 (UniProt: P00747)

PDB	External Database	Details
Ala 741	Ser 760	engineered mutation

B: 14 - 147 (UniProt: P00779)

PDB	External Database	Details
-	His 48	deletion
-	Gly 49	deletion
-	Gly 50	deletion
-	Lys 51	deletion
-	Thr 52	deletion
-	Glu 53	deletion
-	Gln 54	deletion
-	Gly 55	deletion
-	Leu 56	deletion
-	Ser 57	deletion
-	Pro 58	deletion
-	Lys 59	deletion

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	40704.3
Non-Polymers*	Number of molecules	2
	Total formula weight	192.1
All*	Total formula weight	40896.4

*Water molecules are not included.