1L2J

Human Estrogen Receptor beta Ligand-binding Domain in Complex with (R,R)-5,11-cis-diethyl-5,6,11,12-tetrahydrochrysene-2,8-diol

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	ESTROGEN RECEPTOR BETA	polymer	271	30571.1	2	UniProt (Q92731) Pfam (PF00104)	Homo sapiens (human)	ER-BETA, OESTROGEN RECEPTOR BETA
2	C, D (A, B)	(R,R)-5,11-CIS-DIETHYL-5,6,11,12-TETRAHYDROCHRYSENE-2,8-DIOL	non-polymer		320.4	2	Chemie (ETC)
3	E, F (A, B)	water	water		18.0	9	Chemie (HOH)

Sequence modifications

A, B: 256 - 505 (UniProt: Q92731)

PDB	External Database	Details
Met 235	-	expression tag
Gly 236	-	expression tag
Ser 237	-	expression tag
Ser 238	-	expression tag
His 239	-	expression tag
His 240	-	expression tag
His 241	-	expression tag
His 242	-	expression tag
His 243	-	expression tag
His 244	-	expression tag
Ser 245	-	expression tag
Ser 246	-	expression tag
Gly 247	-	expression tag
Leu 248	-	expression tag
Val 249	-	expression tag
Pro 250	-	expression tag
Arg 251	-	expression tag
Gly 252	-	expression tag
Ser 253	-	expression tag
His 254	-	expression tag
Met 255	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	61142.2
Non-Polymers*	Number of molecules	2
	Total formula weight	640.9
All*	Total formula weight	61783.1

*Water molecules are not included.