1KZJ
Crystal Structure of EcTS W80G/dUMP/CB3717 Complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Thymidylate synthase | polymer | 264 | 30430.5 | 6 | UniProt (P0A884) Pfam (PF00303) | Escherichia coli | TS, TSase |
| 2 | G, I, K, M, O... (A, B, C, D, E...) | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE | non-polymer | 308.2 | 6 | Chemie (UMP) PubChem (688) PubChem (65063) PubChem (446899) PubChem (446900) PubChem (57164254) PubChem (71773959) PubChem (92144438) PubChem (92209480) PubChem (92209481) PubChem (92209482) PubChem (92449733) PubChem (133126534) | |||
| 3 | H, J, L, N, P... (A, B, C, D, E...) | 10-PROPARGYL-5,8-DIDEAZAFOLIC ACID | non-polymer | 477.5 | 6 | Chemie (CB3) | |||
| 4 | S, T, U, V, W... (A, B, C, D, E...) | water | water | 18.0 | 292 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F: 1 - 264 (UniProt: P0A884)
| PDB | External Database | Details |
|---|---|---|
| Cxm 1 | Met 1 | modified residue |
| Gly 80 | Trp 80 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 182583.0 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 4713.9 | |
| All* | Total formula weight | 187296.9 |
