1KIE
Inosine-adenosine-guanosine preferring nucleoside hydrolase from Trypanosoma vivax: Asp10Ala mutant in complex with 3-deaza-adenosine
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | inosine-adenosine-guanosine preferring nucleoside hydrolase | polymer | 339 | 37675.0 | 2 | UniProt (Q9GPQ4) Pfam (PF01156) In PDB | Trypanosoma vivax | IAG-NUCLEOSIDE HYDROLASE, IAG-NH |
2 | A, B | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
3 | A | NICKEL (II) ION | non-polymer | 58.7 | 1 | Chemie (NI) | |||
4 | A, B | 3-DEAZA-ADENOSINE | non-polymer | 266.3 | 2 | Chemie (AD3) | |||
5 | water | water | 18.0 | 604 | Chemie (HOH) |
Sequence modifications
A, B: 2 - 327 (UniProt: Q9GPQ4)
PDB | External Database | Details |
---|---|---|
Met -12 | - | expression tag |
Arg -11 | - | expression tag |
Gly -10 | - | expression tag |
Ser -9 | - | expression tag |
Pro -8 | - | expression tag |
His -7 | - | expression tag |
His -6 | - | expression tag |
His -5 | - | expression tag |
His -4 | - | expression tag |
His -3 | - | expression tag |
His -2 | - | expression tag |
Gly -1 | - | expression tag |
Ser 0 | - | expression tag |
Ala 10 | Asp 10 | engineered mutation |
Asn 301 | Lys 301 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 75349.9 | |
Non-Polymers* | Number of molecules | 5 |
Total formula weight | 671.4 | |
All* | Total formula weight | 76021.3 |