1KIE
Inosine-adenosine-guanosine preferring nucleoside hydrolase from Trypanosoma vivax: Asp10Ala mutant in complex with 3-deaza-adenosine
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005829 | cellular_component | cytosol |
| A | 0006139 | biological_process | nucleobase-containing compound metabolic process |
| A | 0006152 | biological_process | purine nucleoside catabolic process |
| A | 0008477 | molecular_function | purine nucleosidase activity |
| A | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| A | 0016799 | molecular_function | hydrolase activity, hydrolyzing N-glycosyl compounds |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0005829 | cellular_component | cytosol |
| B | 0006139 | biological_process | nucleobase-containing compound metabolic process |
| B | 0006152 | biological_process | purine nucleoside catabolic process |
| B | 0008477 | molecular_function | purine nucleosidase activity |
| B | 0016798 | molecular_function | hydrolase activity, acting on glycosyl bonds |
| B | 0016799 | molecular_function | hydrolase activity, hydrolyzing N-glycosyl compounds |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CA A 328 |
| Chain | Residue |
| A | ASP15 |
| A | THR137 |
| A | ASP261 |
| A | AD3801 |
| A | HOH809 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CA B 328 |
| Chain | Residue |
| B | HOH814 |
| B | ASP15 |
| B | THR137 |
| B | ASP261 |
| B | AD3802 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE NI A 701 |
| Chain | Residue |
| A | GLU44 |
| A | GLU113 |
| A | HOH957 |
| site_id | AC4 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE AD3 A 801 |
| Chain | Residue |
| A | ASP14 |
| A | ASP40 |
| A | THR137 |
| A | MET164 |
| A | ASN173 |
| A | GLU184 |
| A | ASN186 |
| A | TRP260 |
| A | ASP261 |
| A | CA328 |
| A | HOH809 |
| site_id | AC5 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE AD3 B 802 |
| Chain | Residue |
| B | ASN12 |
| B | ASP14 |
| B | ASP15 |
| B | ASP40 |
| B | TRP83 |
| B | THR137 |
| B | MET164 |
| B | ASN173 |
| B | GLU184 |
| B | TRP185 |
| B | ASN186 |
| B | TRP260 |
| B | ASP261 |
| B | CA328 |
