1KIC

Inosine-adenosine-guanosine preferring nucleoside hydrolase from Trypanosoma vivax: Asp10Ala mutant in complex with inosine

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	inosine-adenosine-guanosine preferring nucleoside hydrolase	polymer	339	37675.0	2	UniProt (Q9GPQ4) Pfam (PF01156)	Trypanosoma vivax	IAG-NUCLEOSIDE HYDROLASE, IAG-NH
2	C, H (A, B)	CALCIUM ION	non-polymer		40.1	2	Chemie (CA)
3	D (A)	NICKEL (II) ION	non-polymer		58.7	1	Chemie (NI)
4	E, F, G, I (A, B)	INOSINE	non-polymer		268.2	4	Chemie (NOS)
5	J, K (A, B)	water	water		18.0	631	Chemie (HOH)

Sequence modifications

A, B: 2 - 327 (UniProt: Q9GPQ4)

PDB	External Database	Details
Met -12	-	expression tag
Arg -11	-	expression tag
Gly -10	-	expression tag
Ser -9	-	expression tag
Pro -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag
Ala 10	Asp 10	engineered mutation
Asn 301	Lys 301	SEE REMARK 999

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	75349.9
Non-Polymers*	Number of molecules	7
	Total formula weight	1211.8
All*	Total formula weight	76561.7

*Water molecules are not included.