1KIC
Inosine-adenosine-guanosine preferring nucleoside hydrolase from Trypanosoma vivax: Asp10Ala mutant in complex with inosine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | inosine-adenosine-guanosine preferring nucleoside hydrolase | polymer | 339 | 37675.0 | 2 | UniProt (Q9GPQ4) | Trypanosoma vivax | IAG-NUCLEOSIDE HYDROLASE, IAG-NH |
| 2 | C, H (A, B) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) PubChem (271) | |||
| 3 | D (A) | NICKEL (II) ION | non-polymer | 58.7 | 1 | Chemie (NI) PubChem (934) | |||
| 4 | E, F, G, I (A, B) | INOSINE | non-polymer | 268.2 | 4 | Chemie (NOS) PubChem (136164996) PubChem (135398641) PubChem (135402037) PubChem (135403801) PubChem (135410268) PubChem (135440076) PubChem (135522261) PubChem (135530787) PubChem (135600705) PubChem (135604773) PubChem (135768163) PubChem (135768164) PubChem (135768165) PubChem (135828043) PubChem (135885678) PubChem (135905199) PubChem (135914512) PubChem (135920954) PubChem (135928013) PubChem (135956386) PubChem (135992491) PubChem (136026711) PubChem (136162269) PubChem (136265389) PubChem (136500363) PubChem (136590533) PubChem (136614026) PubChem (136623569) PubChem (136624672) PubChem (136663976) PubChem (136704542) PubChem (137295291) PubChem (165413019) PubChem (168265884) PubChem (172873408) PubChem (175577437) | |||
| 5 | J, K (A, B) | water | water | 18.0 | 631 | Chemie (HOH) |
Sequence modifications
A, B: 2 - 327 (UniProt: Q9GPQ4)
| PDB | External Database | Details |
|---|---|---|
| Met -12 | - | expression tag |
| Arg -11 | - | expression tag |
| Gly -10 | - | expression tag |
| Ser -9 | - | expression tag |
| Pro -8 | - | expression tag |
| His -7 | - | expression tag |
| His -6 | - | expression tag |
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
| Ala 10 | Asp 10 | engineered mutation |
| Asn 301 | Lys 301 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 75349.9 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1211.8 | |
| All* | Total formula weight | 76561.7 |
