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1KAV

Human Tyrosine Phosphatase 1B Complexed with an Inhibitor

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
PROTEIN-TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 1polymer29834720.61UniProt (P18031)
Pfam (PF00102)
Homo sapiens (human)PROTEIN-TYROSINE PHOSPHATASE 1B
2B
(A)
[(4-{4-[4-(DIFLUORO-PHOSPHONO-METHYL)-PHENYL]-BUTYL}-PHENYL)-DIFLUORO-METHYL]-PHOSPHONIC ACIDnon-polymer470.31Chemie (FEP)
3C
(A)
waterwater18.0133Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight34720.6
Non-Polymers*Number of molecules1
Total formula weight470.3
All*Total formula weight35190.9
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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