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1K27

Crystal Structure of 5'-Deoxy-5'-Methylthioadenosine Phosphorylase in Complex with a Transition State Analogue

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A5'-Deoxy-5'-Methylthioadenosine Phosphorylasepolymer28331277.11UniProt (Q13126)
Pfam (PF01048)
In PDB
Homo sapiens (human)5'-Methylthioadenosine Phosphorylase, MTAP
2APHOSPHATE IONnon-polymer95.01Chemie (PO4)
3A(3S,4R)-2-(4-AMINO-5H-PYRROLO[3,2-D]PYRIMIDIN-7-YL)-5-[(METHYLSULFANYL)METHYL]PYRROLIDINE-3,4-DIOLnon-polymer297.41Chemie (MTM)
4waterwater18.0138Chemie (HOH)
Sequence modifications
A: 1 - 283 (UniProt: Q13126)
PDBExternal DatabaseDetails
Val 56Ile 56see remark 999
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight31277.1
Non-Polymers*Number of molecules2
Total formula weight392.3
All*Total formula weight31669.4
*Water molecules are not included.

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PDB entries from 2024-07-10

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