1K27
Crystal Structure of 5'-Deoxy-5'-Methylthioadenosine Phosphorylase in Complex with a Transition State Analogue
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | 5'-Deoxy-5'-Methylthioadenosine Phosphorylase | polymer | 283 | 31277.1 | 1 | UniProt (Q13126) Pfam (PF01048) | Homo sapiens (human) | 5'-Methylthioadenosine Phosphorylase, MTAP |
| 2 | B (A) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 3 | C (A) | (3S,4R)-2-(4-AMINO-5H-PYRROLO[3,2-D]PYRIMIDIN-7-YL)-5-[(METHYLSULFANYL)METHYL]PYRROLIDINE-3,4-DIOL | non-polymer | 297.4 | 1 | Chemie (MTM) | |||
| 4 | D (A) | water | water | 18.0 | 138 | Chemie (HOH) |
Sequence modifications
A: 1 - 283 (UniProt: Q13126)
| PDB | External Database | Details |
|---|---|---|
| Val 56 | Ile 56 | see remark 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 31277.1 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 392.3 | |
| All* | Total formula weight | 31669.4 |
