1JWV
Crystal structure of G238A mutant of TEM-1 beta-lactamase in complex with a boronic acid inhibitor (sefb4)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | BETA-LACTAMASE TEM | polymer | 263 | 28956.0 | 1 | UniProt (P62593) Pfam (PF00144) Pfam (PF13354) | Escherichia coli | |
| 2 | B, C, D, E, F (A) | POTASSIUM ION | non-polymer | 39.1 | 5 | Chemie (K) | |||
| 3 | G (A) | PINACOL[[2-AMINO-ALPHA-(1-CARBOXY-1-METHYLETHOXYIMINO)-4-THIAZOLEACETYL]AMINO]METHANEBORONATE | non-polymer | 330.1 | 1 | Chemie (CB4) | |||
| 4 | H (A) | water | water | 18.0 | 417 | Chemie (HOH) |
Sequence modifications
A: 26 - 290 (UniProt: P62593)
| PDB | External Database | Details |
|---|---|---|
| Ala 238 | Gly 236 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 28956.0 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 525.6 | |
| All* | Total formula weight | 29481.6 |
