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1JWH

Crystal Structure of Human Protein Kinase CK2 Holoenzyme

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
Casein kinase II, alpha chainpolymer33740240.92UniProt (P68400)
Pfam (PF00069)
Homo sapiens (human)CK II, catalytic subunit
2C, D
(C, D)
Casein kinase II beta chainpolymer21524969.42UniProt (P67870)
Pfam (PF01214)
Homo sapiens (human)CK II, regulatory subunit
3E, G, H, I, K...
(A, B, C, D)
PHOSPHATE IONnon-polymer95.07Chemie (PO4)
4F
(A)
PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTERnon-polymer506.21Chemie (ANP)
5J, N
(C, D)
ZINC IONnon-polymer65.42Chemie (ZN)
6O, P, Q, R
(A, B, C, D)
waterwater18.0209Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight130420.6
Non-Polymers*Number of molecules10
Total formula weight1301.8
All*Total formula weight131722.4
*Water molecules are not included.

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PDB entries from 2025-07-02

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