1JT5

Human Acidic Fibroblast Growth Factor. 141 Amino Acid Form with Amino Terminal His Tag AND LEU 73 REPLACED BY VAL AND VAL 109 REPLACED BY LEU (L73V/V109L)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	acidic fibroblast growth factor	polymer	146	16686.7	2	UniProt (P05230) Pfam (PF00167) In PDB	Homo sapiens (human)	HEPARIN-BINDING GROWTH FACTOR 1, HBGF-1, AFGF
2	A, B	SULFATE ION	non-polymer		96.1	4	Chemie (SO4)
3		water	water		18.0	217	Chemie (HOH)

Sequence modifications

A, B: 1 - 140 (UniProt: P05230)

PDB	External Database	Details
His 1	-	expression tag
His 1	-	expression tag
His 1	-	expression tag
His 1	-	expression tag
His 1	-	expression tag
His 1	-	expression tag
Val 73	Leu 88	engineered mutation
Leu 109	Val 124	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	33373.5
Non-Polymers*	Number of molecules	4
	Total formula weight	384.3
All*	Total formula weight	33757.7

*Water molecules are not included.