1JPH

Ile260Thr mutant of Human UroD, human uroporphyrinogen III decarboxylase

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	UROPORPHYRINOGEN DECARBOXYLASE	polymer	388	43353.4	1	UniProt (P06132) Pfam (PF01208) In PDB	Homo sapiens (human)	UroD, UPD, uro'gen III decarboxylase
2		water	water		18.0	182	Chemie (HOH)

Sequence modifications

A: 1 - 367 (UniProt: P06132)

PDB	External Database	Details
Met -20	-	expression tag
Gly -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
His -9	-	expression tag
Ser -8	-	expression tag
Ser -7	-	expression tag
Gly -6	-	expression tag
His -5	-	expression tag
Ile -4	-	expression tag
Glu -3	-	expression tag
Gly -2	-	expression tag
Arg -1	-	expression tag
His 0	-	expression tag
Thr 260	Ile 260	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	43353.4
All*	Total formula weight	43353.4

*Water molecules are not included.