1JM7
Solution structure of the BRCA1/BARD1 RING-domain heterodimer
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | BREAST CANCER TYPE 1 SUSCEPTIBILITY PROTEIN | polymer | 112 | 12819.2 | 1 | UniProt (P38398) Pfam (PF00097) | Homo sapiens (human) | BRCA1 |
| 2 | B (B) | BRCA1-ASSOCIATED RING DOMAIN PROTEIN 1 | polymer | 117 | 13169.3 | 1 | UniProt (Q99728) Pfam (PF14835) | Homo sapiens (human) | BARD1 |
| 3 | C, D, E, F (A, B) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) |
Sequence modifications
A: 1 - 110 (UniProt: P38398)
B: 26 - 140 (UniProt: Q99728)
| PDB | External Database | Details |
|---|---|---|
| Gly 111 | - | cloning artifact |
| Lys 112 | - | cloning artifact |
| PDB | External Database | Details |
|---|---|---|
| Gly 141 | - | cloning artifact |
| Lys 142 | - | cloning artifact |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 25988.4 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 261.6 | |
| All* | Total formula weight | 26250.1 |
