1JLU
Crystal Structure of the Catalytic Subunit of cAMP-dependent Protein Kinase Complexed with a Phosphorylated Substrate Peptide and Detergent
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | E | AMP-DEPENDENT PROTEIN KINASE, ALPHA-CATALYTIC SUBUNIT | polymer | 350 | 40657.3 | 1 | UniProt (P05132) Pfam (PF00069) In PDB | Mus musculus (house mouse) | PKA C-ALPHA |
| 2 | S | CAMP-DEPENDENT PROTEIN KINASE INHIBITOR, MUSCLE/BRAIN FORM | polymer | 20 | 2279.4 | 1 | UniProt (P27776) UniProt (by SIFTS) (P61925) In PDB | PKI-ALPHA | |
| 3 | E | N-OCTANE | non-polymer | 114.2 | 1 | Chemie (OCT) | |||
| 4 | water | water | 18.0 | 116 | Chemie (HOH) |
Sequence modifications
S: 361 - 380 (UniProt: P27776)
| PDB | External Database | Details |
|---|---|---|
| Ala 376 | Asn 20 | engineered mutation |
| Sep 377 | Ala 21 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 42936.7 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 114.2 | |
| All* | Total formula weight | 43050.9 |
