1JLE

CRYSTAL STRUCTURE OF Y188C MUTANT HIV-1 REVERSE TRANSCRIPTASE

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	HIV-1 RT, A-CHAIN	polymer	560	64566.9	1	UniProt (P04585) Pfam (PF00078) Pfam (PF06817) Pfam (PF06815) Pfam (PF00075)	HIV-1 M:B_HXB2R
2	B (B)	HIV-1 RT, B-CHAIN	polymer	440	51339.0	1	UniProt (P04585) Pfam (PF00078) Pfam (PF06817) Pfam (PF06815)	HIV-1 M:B_HXB2R
3	C, D (A, B)	water	water		18.0	24	Chemie (HOH)

Sequence modifications

A: 1 - 560 (UniProt: P04585)

PDB	External Database	Details
Csd 188	Tyr 343	engineered mutation
Csd 280	Cys 435	modified residue

B: 1 - 440 (UniProt: P04585)

PDB	External Database	Details
Cys 188	Tyr 343	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	115905.9
All*	Total formula weight	115905.9

*Water molecules are not included.