1JH1
Crystal Structure of MMP-8 complexed with a 6H-1,3,4-thiadiazine derived inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Matrix Metalloproteinase 8 | polymer | 158 | 17612.1 | 1 | UniProt (P22894) Pfam (PF00413) | Homo sapiens (human) | NEUTROPHIL COLLAGENASE |
| 2 | B, C (A) | CALCIUM ION | non-polymer | 40.1 | 2 | Chemie (CA) | |||
| 3 | D, E (A) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 4 | F (A) | BUT-3-ENYL-[5-(4-CHLORO-PHENYL)-3,6-DIHYDRO-[1,3,4]THIADIAZIN-2-YLIDENE]-AMINE | non-polymer | 279.8 | 1 | Chemie (JST) | |||
| 5 | G (A) | water | water | 18.0 | 26 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 17612.1 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 490.8 | |
| All* | Total formula weight | 18102.9 |
