1JG0
Crystal structure of Escherichia coli thymidylate synthase complexed with 2'-deoxyuridine-5'-monophosphate and N,O-didansyl-L-tyrosine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | thymidylate synthase | polymer | 264 | 30387.4 | 2 | UniProt (P0A884) Pfam (PF00303) | Escherichia coli | |
| 2 | C, E (A, B) | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE | non-polymer | 308.2 | 2 | Chemie (UMP) | |||
| 3 | D, F (A, B) | N,O-DIDANSYL-L-TYROSINE | non-polymer | 647.8 | 2 | Chemie (DDT) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 398 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 264 (UniProt: P0A884)
| PDB | External Database | Details |
|---|---|---|
| Cxm 1 | Met 1 | modified residue |
| Ala 21 | Arg 21 | conflict |
| Ala 107 | Arg 107 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 60774.9 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1911.9 | |
| All* | Total formula weight | 62686.8 |
