1JG0

Crystal structure of Escherichia coli thymidylate synthase complexed with 2'-deoxyuridine-5'-monophosphate and N,O-didansyl-L-tyrosine

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	thymidylate synthase	polymer	264	30387.4	2	UniProt (P0A884) Pfam (PF00303) In PDB	Escherichia coli
2	A, B	2'-DEOXYURIDINE 5'-MONOPHOSPHATE	non-polymer		308.2	2	Chemie (UMP)
3	A, B	N,O-DIDANSYL-L-TYROSINE	non-polymer		647.8	2	Chemie (DDT)
4		water	water		18.0	398	Chemie (HOH)

Sequence modifications

A, B: 1 - 264 (UniProt: P0A884)

PDB	External Database	Details
Cxm 1	Met 1	MODIFIED RESIDUE
Ala 21	Arg 21	CONFLICT
Ala 107	Arg 107	CONFLICT

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	60774.9
Non-Polymers*	Number of molecules	4
	Total formula weight	1911.9
All*	Total formula weight	62686.8

*Water molecules are not included.