1JCA
Non-standard Design of Unstable Insulin Analogues with Enhanced Activity
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C | insulin a | polymer | 21 | 2411.8 | 2 | UniProt (P01308) In PDB | ||
2 | B, D | insulin b | polymer | 30 | 3434.0 | 2 | UniProt (P01308) Pfam (PF00049) In PDB | ||
3 | B, D | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
4 | water | water | 18.0 | 36 | Chemie (HOH) |
Sequence modifications
A, C: 1 - 21 (UniProt: P01308)
PDB | External Database | Details |
---|---|---|
Lys 8 | Thr 97 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 4 |
Total formula weight | 11691.5 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 130.8 | |
All* | Total formula weight | 11822.3 |