1JCA
Non-standard Design of Unstable Insulin Analogues with Enhanced Activity
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | insulin a | polymer | 21 | 2411.8 | 2 | UniProt (P01308) | ||
| 2 | B, D (B, D) | insulin b | polymer | 30 | 3434.0 | 2 | UniProt (P01308) Pfam (PF00049) | ||
| 3 | E, F (B, D) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 4 | G, H, I, J (A, B, C, D) | water | water | 18.0 | 36 | Chemie (HOH) |
Sequence modifications
A, C: 1 - 21 (UniProt: P01308)
| PDB | External Database | Details |
|---|---|---|
| Lys 8 | Thr 97 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 11691.5 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 130.8 | |
| All* | Total formula weight | 11822.3 |
