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1J25

Crystal structure of archaeal XPF/Mus81 homolog, Hef from Pyrococcus furiosus, nuclease domain, Mn cocrystal

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
ATP-dependent RNA helicase, putativepolymer14316116.71UniProt (Q8TZH8)
Pfam (PF02732)
Pyrococcus furiosusHef nuclease
2B
(A)
MANGANESE (II) IONnon-polymer54.91Chemie (MN)
3C
(A)
waterwater18.084Chemie (HOH)
Sequence modifications
A: 2 - 143 (UniProt: Q8TZH8)
PDBExternal DatabaseDetails
Met 1-initiating methionine
Leu 55Phe 601engineered mutation
Gly 63Arg 609engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight16116.7
Non-Polymers*Number of molecules1
Total formula weight54.9
All*Total formula weight16171.6
*Water molecules are not included.

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PDB entries from 2025-06-18

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