1J1D
Crystal structure of the 46kDa domain of human cardiac troponin in the Ca2+ saturated form
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D (A, D) | Troponin C | polymer | 161 | 18401.4 | 2 | UniProt (P63316) Pfam (PF13833) Pfam (PF13499) | Homo sapiens (human) | TNC |
| 2 | B, E (B, E) | Troponin T | polymer | 106 | 12842.8 | 2 | UniProt (P45379) Pfam (PF00992) | Homo sapiens (human) | TnT |
| 3 | C, F (C, F) | Troponin I | polymer | 133 | 15191.7 | 2 | UniProt (P19429) Pfam (PF00992) | Homo sapiens (human) | TNI |
| 4 | G, H, I, J, K... (A, D) | CALCIUM ION | non-polymer | 40.1 | 6 | Chemie (CA) | |||
| 5 | M, N, O, P, Q... (A, B, C, D, E...) | water | water | 18.0 | 102 | Chemie (HOH) |
Sequence modifications
A, D: 1 - 161 (UniProt: P63316)
C, F: 31 - 163 (UniProt: P19429)
| PDB | External Database | Details |
|---|---|---|
| Ser 35 | Cys 35 | engineered mutation |
| Ser 84 | Cys 84 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Met 31 | Thr 30 | engineered mutation |
| Ala 80 | Cys 79 | engineered mutation |
| Ala 97 | Cys 96 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 92871.7 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 240.5 | |
| All* | Total formula weight | 93112.2 |
