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1IZH

Inhibitor of HIV protease with unusual binding mode potently inhibiting multi-resistant protease mutants

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
proteinasepolymer9910830.82UniProt (Q90EB9)Human immunodeficiency virus 1protease
2C
(B)
{(1S)-1-BENZYL-4-[3-CARBAMOYL-1-(1-CARBAMOYL-2-PHENYL-ETHYLCARBAMOYL)-(S)-PROPYLCARBAMOYL]-2-OXO-5-PHENYL-PENTYL}-CARBAMIC ACID TERT-BUTYL ESTERnon-polymer685.81Chemie (Q50)
3D, E
(A, B)
waterwater18.0221Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight21661.6
Non-Polymers*Number of molecules1
Total formula weight685.8
All*Total formula weight22347.4
*Water molecules are not included.

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PDB entries from 2026-03-25

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