1IR3
PHOSPHORYLATED INSULIN RECEPTOR TYROSINE KINASE IN COMPLEX WITH PEPTIDE SUBSTRATE AND ATP ANALOG
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | INSULIN RECEPTOR | polymer | 306 | 35032.7 | 1 | UniProt (P06213) Pfam (PF07714) | Homo sapiens (human) | |
| 2 | B (B) | PEPTIDE SUBSTRATE | polymer | 18 | 1955.3 | 1 | |||
| 3 | C, D (A) | MAGNESIUM ION | non-polymer | 24.3 | 2 | Chemie (MG) | |||
| 4 | E (A) | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | non-polymer | 506.2 | 1 | Chemie (ANP) | |||
| 5 | F, G (A, B) | water | water | 18.0 | 202 | Chemie (HOH) |
Sequence modifications
A: 978 - 1283 (UniProt: P06213)
| PDB | External Database | Details |
|---|---|---|
| Ser 981 | Cys 1008 | engineered mutation |
| Phe 984 | Tyr 1011 | engineered mutation |
| Ptr 1158 | Tyr 1185 | modified residue |
| Ptr 1162 | Tyr 1189 | modified residue |
| Ptr 1163 | Tyr 1190 | modified residue |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 36988.0 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 554.8 | |
| All* | Total formula weight | 37542.8 |
