1IJR
Crystal structure of LCK SH2 complexed with nonpeptide phosphotyrosine mimetic
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | PROTO-ONCOGENE TYROSINE-PROTEIN KINASE LCK | polymer | 104 | 11830.2 | 1 | UniProt (P06239) Pfam (PF00017) In PDB | Homo sapiens (human) | |
| 2 | A | (4-{2-ACETYLAMINO-2-[1-(3-CARBAMOYL-4-CYCLOHEXYLMETHOXY-PHENYL)-ETHYLCARBAMOYL}-ETHYL}-2-PHOSPHONO-PHENOXY)-ACETIC ACID | non-polymer | 619.6 | 1 | Chemie (CC0) |
Sequence modifications
A: 1 - 104 (UniProt: P06239)
| PDB | External Database | Details |
|---|---|---|
| Ala 1 | Glu 123 | conflict |
| Cys 42 | Ser 164 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 11830.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 619.6 | |
| All* | Total formula weight | 12449.8 |
