1IJR
Crystal structure of LCK SH2 complexed with nonpeptide phosphotyrosine mimetic
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE CC0 A 150 |
| Chain | Residue |
| A | LEU10 |
| A | CYS42 |
| A | HIS58 |
| A | TYR59 |
| A | LYS60 |
| A | ILE71 |
| A | GLY93 |
| A | ARG12 |
| A | ASP14 |
| A | ARG17 |
| A | GLN18 |
| A | ARG32 |
| A | SER34 |
| A | GLU35 |
| A | SER36 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 97 |
| Details | Domain: {"description":"SH2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00191","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"19690332","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"19690332","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphotyrosine","evidences":[{"source":"UniProtKB","id":"P06240","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
