1IGW
Crystal Structure of the Isocitrate Lyase from the A219C mutant of Escherichia coli
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Isocitrate lyase | polymer | 434 | 47598.4 | 4 | UniProt (P0A9G6) Pfam (PF00463) | Escherichia coli | ISOCITRASE, ISOCITRATASE, ICL |
| 2 | AA, BA, CA, DA, E... (D, A, B, C) | MERCURY (II) ION | non-polymer | 200.6 | 21 | Chemie (HG) | |||
| 3 | FA, J, Q, Y (D, A, B, C) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
| 4 | GA, K, R, Z (D, A, B, C) | PYRUVIC ACID | non-polymer | 88.1 | 4 | Chemie (PYR) | |||
| 5 | HA, IA, JA, KA (A, B, C, D) | water | water | 18.0 | 767 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 434 (UniProt: P0A9G6)
| PDB | External Database | Details |
|---|---|---|
| Cys 219 | Ala 219 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 190393.6 | |
| Non-Polymers* | Number of molecules | 29 |
| Total formula weight | 4661.9 | |
| All* | Total formula weight | 195055.4 |
