1IG9
Structure of the Replicating Complex of a Pol Alpha Family DNA Polymerase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (T) | 5'-D(*AP*CP*AP*GP*GP*TP*AP*AP*GP*CP*AP*GP*TP*CP*CP*GP*CP*G)-3' | polymer | 18 | 5550.6 | 1 | |||
| 2 | B (P) | 5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*CP*(DOC))-3' | polymer | 14 | 4240.8 | 1 | |||
| 3 | C (A) | DNA POLYMERASE | polymer | 903 | 104655.1 | 1 | UniProt (Q38087) Pfam (PF03104) Pfam (PF00136) | Enterobacteria phage RB69 | |
| 4 | D, E, F, G (A) | CALCIUM ION | non-polymer | 40.1 | 4 | Chemie (CA) | |||
| 5 | H (A) | THYMIDINE-5'-TRIPHOSPHATE | non-polymer | 482.2 | 1 | Chemie (TTP) | |||
| 6 | I, J, K (T, P, A) | water | water | 18.0 | 356 | Chemie (HOH) |
Sequence modifications
A: 1 - 903 (UniProt: Q38087)
| PDB | External Database | Details |
|---|---|---|
| Ala 222 | Asp 222 | engineered mutation |
| Ala 327 | Asp 327 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 114446.5 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 642.5 | |
| All* | Total formula weight | 115089.0 |
