1I7M

HUMAN S-ADENOSYLMETHIONINE DECARBOXYLASE WITH COVALENTLY BOUND PYRUVOYL GROUP AND COMPLEXED WITH 4-AMIDINOINDAN-1-ONE-2'-AMIDINOHYDRAZONE

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (B, D)	S-ADENOSYLMETHIONINE DECARBOXYLASE BETA CHAIN	polymer	67	7741.5	2	UniProt (P17707)	Homo sapiens (human)
2	B, D (A, C)	S-ADENOSYLMETHIONINE DECARBOXYLASE ALPHA CHAIN	polymer	267	31187.8	2	UniProt (P17707) Pfam (PF01536)	Homo sapiens (human)
3	E, G (B, D)	1,4-DIAMINOBUTANE	non-polymer		88.2	2	Chemie (PUT)
4	F, H (A, D)	4-AMIDINOINDAN-1-ONE-2'-AMIDINOHYDRAZONE	non-polymer		230.3	2	Chemie (CG)
5	I, J, K, L (B, A, D, C)	water	water		18.0	243	Chemie (HOH)

Sequence modifications

B, D: 1 - 67 (UniProt: P17707)

PDB	External Database	Details
Mse 1	Met 1	modified residue

A, C: 68 - 334 (UniProt: P17707)

PDB	External Database	Details
Pyr 68	Ser 68	SEE REMARK 999
Mse 70	Met 70	modified residue
Mse 118	Met 118	modified residue
Mse 149	Met 149	modified residue
Mse 152	Met 152	modified residue
Mse 181	Met 181	modified residue
Mse 189	Met 189	modified residue
Mse 194	Met 194	modified residue
Mse 222	Met 222	modified residue
Mse 230	Met 230	modified residue
Mse 233	Met 233	modified residue
Mse 314	Met 314	modified residue

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	77858.6
Non-Polymers*	Number of molecules	4
	Total formula weight	636.8
All*	Total formula weight	78495.4

*Water molecules are not included.