1I1C

NON-FCRN BINDING FC FRAGMENT OF RAT IGG2A

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	IG GAMMA-2A CHAIN C REGION	polymer	239	26650.9	2	UniProt (P20760) Pfam (PF07654) In PDB	Rattus norvegicus (Norway rat)	IGG2A
2	C	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		1463.3	1	In PDB GlyTouCan (G59451NL)
3	D	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose	branched		1463.3	1	In PDB GlyTouCan (G80858MF)

Sequence modifications

A, B: 223 - 447 (UniProt: P20760)

PDB	External Database	Details
Gly 252	Thr 127	engineered mutation
Gly 253	Ile 128	engineered mutation
Gly 254	Thr 129	engineered mutation
Glu 310	His 185	engineered mutation
Glu 433	His 308	engineered mutation
Glu 435	His 310	engineered mutation
Gly 448	-	cloning artifact
Ile 449	-	cloning artifact
Glu 450	-	cloning artifact
Gly 451	-	cloning artifact
Arg 452	-	cloning artifact
Gly 453	-	cloning artifact
Ser 454	-	cloning artifact
Ser 455	-	cloning artifact
His 456	-	cloning artifact
His 457	-	cloning artifact
His 458	-	cloning artifact
His 459	-	cloning artifact
His 460	-	cloning artifact
His 461	-	cloning artifact

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	53301.7
Branched	Number of molecules	2
	Total formula weight	2926.7
All*	Total formula weight	56228.4

*Water molecules are not included.