1HVK
INFLUENCE OF STEREOCHEMISTRY ON ACTIVITY AND BINDING MODES FOR C2 SYMMETRY-BASED DIOL INHIBITORS OF HIV-1 PROTEASE
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | HIV-1 PROTEASE | polymer | 99 | 10803.8 | 2 | UniProt (P03366) | Human immunodeficiency virus 1 | |
| 2 | C (A) | N-{1-BENZYL-(2S,3S)-2,3-DIHYDROXY-4-[3-METHYL-2-(3-METHYL-3-PYRIDIN-2-YLMETHYL-UREIDO)-BUTYRYLAMINO]-5-PHENYL-PENTYL}-3-METHYL-2-(3-METHYL-3-PYRIDIN-2-YLMETHYL-UREIDO)-BUTYRAMIDE | non-polymer | 795.0 | 1 | Chemie (A79) PubChem (44340246) PubChem (72357) PubChem (44340360) PubChem (44340527) PubChem (44568721) PubChem (466188) PubChem (54240793) PubChem (67681938) PubChem (4470975) PubChem (64999) PubChem (446148) PubChem (466189) PubChem (100948702) PubChem (10259715) | |||
| 3 | D (A) | water | water | 18.0 | 1 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 21607.5 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 795.0 | |
| All* | Total formula weight | 22402.5 |
